diagnosis early in pregnancy will reveal if the fetus has Tay-Sachs or Canavan disease. Chronic Hexosaminidase A deficiency usually develops before age 10 but people do not lose as many motor skills as those with Tay-Sachs. Gradually, Tay-Sachs children lose motor skills and mental functions. Non-Jewish French Canadians living near the. Some people have just one normal copy of the gene, and they still make enough Hex-A protein to keep the brain and spinal cord healthy. Defects in a gene called hexa cause Tay-Sachs. Over time, the child becomes blind, deaf, mentally retarded, paralyzed and non responsive to the environment.
Tay-Sachs disease is a rare inherited disorder that progressively d estroys nerve cells (neurons) in the brain and spinal cord.
Tay-Sachs disease causes a progressive deterioration of nerve cells and of mental and physical abilities that begins around six months of age.
Answers to frequently asked questions about Tay-Sachs disease, published by the Na tional Human Genome Research Institute.
Tay-Sachs disease is a rare, inherited condition affecting the ner ve cells.
This ongoing accumulation causes progressive damage to the cells. Continued Tay-Sachs Later in Life Theres an even rarer type of Tay-Sachs called late onset or adult onset. Life expectancy can vary widely and may not be shortened. Tay-Sachs carriers are found most frequently among families of eastern European Jewish descent (Ashkenazi Jews). Cognitive and verbal skills are affected later in the course. Late-onset Tay-Sachs doesn't always shorten life span.
TaySachs disease - Wikipedia Tay-Sachs disease - Genetics Home Reference - NIH